9eq6
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cachd1 and FZD5 complex== | |
| - | + | <StructureSection load='9eq6' size='340' side='right'caption='[[9eq6]], [[Resolution|resolution]] 2.72Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9eq6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EQ6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.72Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[Category: Jones | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9eq6 OCA], [https://pdbe.org/9eq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9eq6 RCSB], [https://www.ebi.ac.uk/pdbsum/9eq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9eq6 ProSAT]</span></td></tr> |
| - | [[Category: Ren | + | </table> |
| - | [[Category: Zhao | + | == Function == |
| + | [https://www.uniprot.org/uniprot/FZD5_MOUSE FZD5_MOUSE] Receptor for Wnt proteins (PubMed:11092808, PubMed:18230341). Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:18230341). In vitro activates WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 signaling (PubMed:11092808). In neurons, activation by WNT7A promotes formation of synapses (By similarity). May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable). Plays a role in yolk sac angiogenesis and in placental vascularization (PubMed:11092808). Plays a role in ocular development (By similarity).[UniProtKB:Q13467]<ref>PMID:11092808</ref> <ref>PMID:18230341</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Jones EY]] | ||
| + | [[Category: Ren J]] | ||
| + | [[Category: Zhao Y]] | ||
Current revision
Cachd1 and FZD5 complex
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