9izd
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human HCAR1-Gi complex with CHBA== | |
| - | + | <StructureSection load='9izd' size='340' side='right'caption='[[9izd]], [[Resolution|resolution]] 3.16Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9izd]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IZD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.16Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1D71:3-chloranyl-5-oxidanyl-benzoic+acid'>A1D71</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9izd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9izd OCA], [https://pdbe.org/9izd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9izd RCSB], [https://www.ebi.ac.uk/pdbsum/9izd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9izd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HCAR1_HUMAN HCAR1_HUMAN] Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.<ref>PMID:19047060</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fang Y]] | ||
| + | [[Category: Xin P]] | ||
Current revision
Cryo-EM structure of human HCAR1-Gi complex with CHBA
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