We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
User:Elizabeth Yowell/ SandboxFinal
From Proteopedia
(Difference between revisions)
| Line 14: | Line 14: | ||
===AHB2 and LCB1/LCB3 Specifically=== | ===AHB2 and LCB1/LCB3 Specifically=== | ||
| - | + | Protein inhibitors were thought of as a new idea for creating vaccines <ref name="Cao">DOI:10.1126/science.abd9909</ref>. | |
[[Image:ACB1_Methodology.png|400 px|left|thumb|The use of the Rosetta Blueprint protein design to create the AHB2 inhibitor.]] | [[Image:ACB1_Methodology.png|400 px|left|thumb|The use of the Rosetta Blueprint protein design to create the AHB2 inhibitor.]] | ||
| + | |||
| + | |||
[[Image:LCB1_Methodology.png|400 px|left|thumb|The use of the De Novo protein design to create the LCB1 and LCB3 inhibitors.]] | [[Image:LCB1_Methodology.png|400 px|left|thumb|The use of the De Novo protein design to create the LCB1 and LCB3 inhibitors.]] | ||
| + | |||
| + | |||
| + | |||
| + | |||
| + | |||
| + | |||
| + | |||
| Line 43: | Line 52: | ||
==References== | ==References== | ||
| + | Cao, L., Goreshnik, I., Coventry, B., Case, J.B., Miller, L., Kozodoy, L., Chen, R.E., Carter, L., Walls, A.C., Park, Y., Strauch, E., Stewart, L., Diamond, M.S., Veesler, D., & Baker, D. De novo design of picomolar SARS-CoV-2 mini protein inhibitors. Science 370, 426-431 (2020). https://doi.org/10.1126/science.abd9909 | ||
===PDB Files=== | ===PDB Files=== | ||
Revision as of 20:45, 2 April 2025
Contents |
SARS CoV-2 Protein Inhibitors (AHB2 and LCB1/LCB3)
| |||||||||||
References
Cao, L., Goreshnik, I., Coventry, B., Case, J.B., Miller, L., Kozodoy, L., Chen, R.E., Carter, L., Walls, A.C., Park, Y., Strauch, E., Stewart, L., Diamond, M.S., Veesler, D., & Baker, D. De novo design of picomolar SARS-CoV-2 mini protein inhibitors. Science 370, 426-431 (2020). https://doi.org/10.1126/science.abd9909
PDB Files
[1]https://www.rcsb.org/structure/7UHB
Student Contributors
- Giavanna Yowell
- Shea Bailey
- Matthew Pereira
