8qna

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Current revision (07:43, 9 April 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8qna is ON HOLD until Paper Publication
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==OPR3 variant - R366A==
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<StructureSection load='8qna' size='340' side='right'caption='[[8qna]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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Authors: Bijelic, A., Macheroux, P., Kerschbaumer, B.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8qna]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QNA FirstGlance]. <br>
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Description: OPR3 variant -R366A
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Kerschbaumer, B]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qna OCA], [https://pdbe.org/8qna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qna RCSB], [https://www.ebi.ac.uk/pdbsum/8qna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qna ProSAT]</span></td></tr>
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[[Category: Macheroux, P]]
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</table>
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[[Category: Bijelic, A]]
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== Function ==
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[https://www.uniprot.org/uniprot/OPR3_SOLLC OPR3_SOLLC] Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. It is required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program (By similarity). In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Solanum lycopersicum]]
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[[Category: Bijelic A]]
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[[Category: Kerschbaumer B]]
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[[Category: Macheroux P]]

Current revision

OPR3 variant - R366A

PDB ID 8qna

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