8qne

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Current revision (07:43, 9 April 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8qne is ON HOLD until Paper Publication
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==OPR3 variant with redesigned loop 6 (9aa)==
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<StructureSection load='8qne' size='340' side='right'caption='[[8qne]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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Authors: Bijelic, A., Macheroux, P., Kerschbaumer, B.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8qne]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QNE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QNE FirstGlance]. <br>
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Description: OPR3 variant with redesigned loop 6 (9aa)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Kerschbaumer, B]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qne OCA], [https://pdbe.org/8qne PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qne RCSB], [https://www.ebi.ac.uk/pdbsum/8qne PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qne ProSAT]</span></td></tr>
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[[Category: Macheroux, P]]
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</table>
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[[Category: Bijelic, A]]
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== Function ==
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[https://www.uniprot.org/uniprot/OPR3_SOLLC OPR3_SOLLC] Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. It is required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program (By similarity). In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Solanum lycopersicum]]
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[[Category: Bijelic A]]
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[[Category: Kerschbaumer B]]
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[[Category: Macheroux P]]

Current revision

OPR3 variant with redesigned loop 6 (9aa)

PDB ID 8qne

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