9d9v
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==X-Ray structure of ALX4 homeodomain== | |
| - | + | <StructureSection load='9d9v' size='340' side='right'caption='[[9d9v]], [[Resolution|resolution]] 2.39Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9d9v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9D9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9D9V FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.39Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
| - | [[Category: Kovall | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9d9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9d9v OCA], [https://pdbe.org/9d9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9d9v RCSB], [https://www.ebi.ac.uk/pdbsum/9d9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9d9v ProSAT]</span></td></tr> |
| - | [[Category: Yuan | + | </table> |
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/ALX4_HUMAN ALX4_HUMAN] Isolated scaphocephaly;Parietal foramina;Frontonasal dysplasia with alopecia and genital anomaly;Potocki-Shaffer syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Disease susceptibility is associated with variations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ALX4_HUMAN ALX4_HUMAN] Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development.<ref>PMID:19692347</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kovall RA]] | ||
| + | [[Category: Yuan Z]] | ||
Current revision
X-Ray structure of ALX4 homeodomain
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