9g0w

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Current revision (08:05, 9 April 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9g0w is ON HOLD until Paper Publication
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==auxin transporter PIN8 as asymmetric dimer (inward/outward) with 2,4-D bound in the inward vestibule prebinding state==
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<StructureSection load='9g0w' size='340' side='right'caption='[[9g0w]], [[Resolution|resolution]] 3.54&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9g0w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9G0W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9G0W FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.54&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CFA:(2,4-DICHLOROPHENOXY)ACETIC+ACID'>CFA</scene>, <scene name='pdbligand=DLP:1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>DLP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9g0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9g0w OCA], [https://pdbe.org/9g0w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9g0w RCSB], [https://www.ebi.ac.uk/pdbsum/9g0w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9g0w ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PIN8_ARATH PIN8_ARATH] Component of the intracellular auxin-transport pathway in the male gametophyte (PubMed:20439545, PubMed:22540348). Involved in the regulation of auxin homeostasis in pollen (PubMed:22540348). Involved in the efflux of auxin from the endoplasmic reticulum into the cytoplasm (PubMed:22760640). PIN5 and PIN8 may have an antagonistic/compensatory activity (PubMed:22760640, PubMed:22990451). Involved in the control of vein patterning (PubMed:23437008, PubMed:24304505). Redundantly with PIN6, inhibits the vein-formation-promoting functions of PIN5 (PubMed:26560462). PIN5, PIN6, and PIN8 control vein network geometry, but they are expressed in mutually exclusive domains of leaf vascular cells (PubMed:26560462).<ref>PMID:20439545</ref> <ref>PMID:22540348</ref> <ref>PMID:22760640</ref> <ref>PMID:23437008</ref> <ref>PMID:24304505</ref> <ref>PMID:26560462</ref> <ref>PMID:22990451</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Arabidopsis thaliana]]
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[[Category: Large Structures]]
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[[Category: Pedersen BP]]
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[[Category: Stokes DL]]
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[[Category: Ung KL]]

Current revision

auxin transporter PIN8 as asymmetric dimer (inward/outward) with 2,4-D bound in the inward vestibule prebinding state

PDB ID 9g0w

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