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| | <StructureSection load='6r2q' size='340' side='right'caption='[[6r2q]], [[Resolution|resolution]] 2.70Å' scene=''> | | <StructureSection load='6r2q' size='340' side='right'caption='[[6r2q]], [[Resolution|resolution]] 2.70Å' scene=''> |
| | == Structural highlights == | | == Structural highlights == |
| - | <table><tr><td colspan='2'>[[6r2q]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Shewanella_baltica Shewanella baltica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R2Q OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6R2Q FirstGlance]. <br> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6R2Q FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.697Å</td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qyc|6qyc]]</td></tr> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6r2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r2q OCA], [http://pdbe.org/6r2q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r2q RCSB], [http://www.ebi.ac.uk/pdbsum/6r2q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r2q ProSAT]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6r2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r2q OCA], [https://pdbe.org/6r2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6r2q RCSB], [https://www.ebi.ac.uk/pdbsum/6r2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6r2q ProSAT]</span></td></tr> |
| | </table> | | </table> |
| | <div style="background-color:#fffaf0;"> | | <div style="background-color:#fffaf0;"> |
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| | </div> | | </div> |
| | <div class="pdbe-citations 6r2q" style="background-color:#fffaf0;"></div> | | <div class="pdbe-citations 6r2q" style="background-color:#fffaf0;"></div> |
| | + | |
| | + | ==See Also== |
| | + | *[[Cystathionine ò-synthase 3D structures|Cystathionine ò-synthase 3D structures]] |
| | == References == | | == References == |
| | <references/> | | <references/> |
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| | </StructureSection> | | </StructureSection> |
| | [[Category: Large Structures]] | | [[Category: Large Structures]] |
| - | [[Category: Shewanella baltica]]
| + | [[Category: Clarke TA]] |
| - | [[Category: Clarke, T A]] | + | [[Category: Edwards MJ]] |
| - | [[Category: Edwards, M J]] | + | |
| - | [[Category: Cytochrome]]
| + | |
| - | [[Category: Electron transport]]
| + | |
| - | [[Category: Greek key]]
| + | |
| - | [[Category: Membrane protein]]
| + | |
| - | [[Category: Multiheme]]
| + | |
| Structural highlights
Publication Abstract from PubMed
A growing number of bacteria are recognized to conduct electrons across their cell envelope, and yet molecular details of the mechanisms supporting this process remain unknown. Here, we report the atomic structure of an outer membrane spanning protein complex, MtrAB, that is representative of a protein family known to transport electrons between the interior and exterior environments of phylogenetically and metabolically diverse microorganisms. The structure is revealed as a naturally insulated biomolecular wire possessing a 10-heme cytochrome, MtrA, insulated from the membrane lipidic environment by embedding within a 26 strand beta-barrel formed by MtrB. MtrAB forms an intimate connection with an extracellular 10-heme cytochrome, MtrC, which presents its hemes across a large surface area for electrical contact with extracellular redox partners, including transition metals and electrodes.
The Crystal Structure of a Biological Insulated Transmembrane Molecular Wire.,Edwards MJ, White GF, Butt JN, Richardson DJ, Clarke TA Cell. 2020 Apr 8. pii: S0092-8674(20)30325-1. doi: 10.1016/j.cell.2020.03.032. PMID:32289252[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Edwards MJ, White GF, Butt JN, Richardson DJ, Clarke TA. The Crystal Structure of a Biological Insulated Transmembrane Molecular Wire. Cell. 2020 Apr 8. pii: S0092-8674(20)30325-1. doi: 10.1016/j.cell.2020.03.032. PMID:32289252 doi:http://dx.doi.org/10.1016/j.cell.2020.03.032
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