7cgp
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Cryo-EM structure of the human mitochondrial translocase TIM22 complex at 3.7 angstrom.== |
| - | <StructureSection load='7cgp' size='340' side='right'caption='[[7cgp]]' scene=''> | + | <StructureSection load='7cgp' size='340' side='right'caption='[[7cgp]], [[Resolution|resolution]] 3.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7cgp]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CGP FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cgp OCA], [https://pdbe.org/7cgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cgp RCSB], [https://www.ebi.ac.uk/pdbsum/7cgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cgp ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEE:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>PEE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cgp OCA], [https://pdbe.org/7cgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cgp RCSB], [https://www.ebi.ac.uk/pdbsum/7cgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cgp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/TIM22_HUMAN TIM22_HUMAN] The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TIM22_HUMAN TIM22_HUMAN] Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).[UniProtKB:Q12328] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Diacylglycerol kinase 3D structures|Diacylglycerol kinase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Z | + | [[Category: Guan Z]] |
| + | [[Category: Qi L]] | ||
| + | [[Category: Wang Q]] | ||
| + | [[Category: Yan C]] | ||
| + | [[Category: Yin P]] | ||
Current revision
Cryo-EM structure of the human mitochondrial translocase TIM22 complex at 3.7 angstrom.
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Categories: Homo sapiens | Large Structures | Guan Z | Qi L | Wang Q | Yan C | Yin P
