9ew3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:21, 16 April 2025) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 9ew3 is ON HOLD until Paper Publication
+
==Ternary structure of 14-3-3s, C-RAF phosphopeptide 12-mer (pS259) and compound 78 (1084378)==
-
 
+
<StructureSection load='9ew3' size='340' side='right'caption='[[9ew3]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
-
Authors: Konstantinidou, M., Vickery, H., Pennings, M.A.M., Virta, J., Visser, E.J., Oetelaar, M.C.M., Overmans, M., Neitz, J., Ottmann, C., Brunsveld, L., Arkin, M.R.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[9ew3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EW3 FirstGlance]. <br>
-
Description: Ternary structure of 14-3-3s, C-RAF phosphopeptide 12-mer (pS259) and compound 78 (1084378)
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=WQN:1-[8-(4-bromophenyl)sulfonyl-5-oxa-2,8-diazaspiro[3.5]nonan-2-yl]-2-chloranyl-ethanone'>WQN</scene></td></tr>
-
[[Category: Konstantinidou, M]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ew3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ew3 OCA], [https://pdbe.org/9ew3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ew3 RCSB], [https://www.ebi.ac.uk/pdbsum/9ew3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ew3 ProSAT]</span></td></tr>
-
[[Category: Arkin, M.R]]
+
</table>
-
[[Category: Overmans, M]]
+
== Function ==
-
[[Category: Pennings, M.A.M]]
+
[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.
-
[[Category: Virta, J]]
+
__TOC__
-
[[Category: Visser, E.J]]
+
</StructureSection>
-
[[Category: Neitz, J]]
+
[[Category: Homo sapiens]]
-
[[Category: Ottmann, C]]
+
[[Category: Large Structures]]
-
[[Category: Oetelaar, M.C.M]]
+
[[Category: Arkin MR]]
-
[[Category: Brunsveld, L]]
+
[[Category: Brunsveld L]]
-
[[Category: Vickery, H]]
+
[[Category: Konstantinidou M]]
 +
[[Category: Neitz J]]
 +
[[Category: Oetelaar MCM]]
 +
[[Category: Ottmann C]]
 +
[[Category: Overmans M]]
 +
[[Category: Pennings MAM]]
 +
[[Category: Vickery H]]
 +
[[Category: Virta J]]
 +
[[Category: Visser EJ]]

Current revision

Ternary structure of 14-3-3s, C-RAF phosphopeptide 12-mer (pS259) and compound 78 (1084378)

PDB ID 9ew3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/9ew3"
Personal tools