9ew8
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Discovery of a Series of Covalent, Cell Active Bfl-1 Inhibitors== | |
| - | + | <StructureSection load='9ew8' size='340' side='right'caption='[[9ew8]], [[Resolution|resolution]] 1.49Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9ew8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EW8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.488Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1H7Q:1-[(2~{R})-2-phenylpyrrolidin-1-yl]propan-1-one'>A1H7Q</scene></td></tr> |
| - | [[Category: Hargreaves | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ew8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ew8 OCA], [https://pdbe.org/9ew8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ew8 RCSB], [https://www.ebi.ac.uk/pdbsum/9ew8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ew8 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/B2LA1_HUMAN B2LA1_HUMAN] Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hargreaves D]] | ||
Current revision
Discovery of a Series of Covalent, Cell Active Bfl-1 Inhibitors
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