User:Peyton Jenkins/Sandbox 1
From Proteopedia
(Difference between revisions)
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=== STK11: === | === STK11: === | ||
[[STK11]] can be broken down into 3 domains. An N-terminal domain (aa 1-42), kinase domain (aa 43-347), and a C-terminal domain (aa 348-433). The activation loop of [[STK11]] is located from residues ~202-212. Within the activation loop is P204, which interacts with a hydrophobic pocket on MO25, which is necessary to stabilize the active conformation. | [[STK11]] can be broken down into 3 domains. An N-terminal domain (aa 1-42), kinase domain (aa 43-347), and a C-terminal domain (aa 348-433). The activation loop of [[STK11]] is located from residues ~202-212. Within the activation loop is P204, which interacts with a hydrophobic pocket on MO25, which is necessary to stabilize the active conformation. | ||
| - | === | + | === STRADα === |
| - | The | + | The WEF motif (aa 429-431) on the C-terminus of STRADα with the C-terminus of MO25 interacts . |
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 00:23, 29 April 2025
2WTK: Hetertrimeric Complex of STK11, MO25, and STRADα
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