8z8w
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of EphA6/Caskin1 complex== | |
| - | + | <StructureSection load='8z8w' size='340' side='right'caption='[[8z8w]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8z8w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z8W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z8W FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z8w OCA], [https://pdbe.org/8z8w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z8w RCSB], [https://www.ebi.ac.uk/pdbsum/8z8w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z8w ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CSKI1_MOUSE CSKI1_MOUSE] May link the scaffolding protein CASK to downstream intracellular effectors.[https://www.uniprot.org/uniprot/EPHA6_MOUSE EPHA6_MOUSE] Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Li J]] | ||
| + | [[Category: Liu W]] | ||
Current revision
Crystal Structure of EphA6/Caskin1 complex
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