9hft
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human CDADC1 inactive mutant (E400A): hexamer with 5mdCTP bound in the active site== | |
| - | + | <StructureSection load='9hft' size='340' side='right'caption='[[9hft]], [[Resolution|resolution]] 2.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9hft]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HFT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1I2I:[[(2~{R},3~{S},5~{R})-5-(4-azanyl-5-methyl-2-oxidanylidene-pyrimidin-1-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+phosphono+hydrogen+phosphate'>A1I2I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hft OCA], [https://pdbe.org/9hft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hft RCSB], [https://www.ebi.ac.uk/pdbsum/9hft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hft ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CDAC1_HUMAN CDAC1_HUMAN] Catalyzes the deamination of cytidine and deoxycytidine into uridine and deoxyuridine, respectively (PubMed:26945630). May play an important role in testicular development and spermatogenesis (PubMed:16955368).<ref>PMID:16955368</ref> <ref>PMID:26945630</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bochtler M]] | ||
| + | [[Category: Czarnocki-Cieciura M]] | ||
| + | [[Category: Kanai T]] | ||
| + | [[Category: Lountos G]] | ||
| + | [[Category: Rathore I]] | ||
| + | [[Category: Skowronek K]] | ||
| + | [[Category: Slyvka A]] | ||
| + | [[Category: Wang Z]] | ||
| + | [[Category: Wlodawer A]] | ||
| + | [[Category: Yang R]] | ||
Current revision
Cryo-EM structure of human CDADC1 inactive mutant (E400A): hexamer with 5mdCTP bound in the active site
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Categories: Homo sapiens | Large Structures | Bochtler M | Czarnocki-Cieciura M | Kanai T | Lountos G | Rathore I | Skowronek K | Slyvka A | Wang Z | Wlodawer A | Yang R
