JMS/Sandbox/msn2
From Proteopedia
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The precise interaction with DNA likely involves specific residues within these fingers making contact with the STRE sequence. | The precise interaction with DNA likely involves specific residues within these fingers making contact with the STRE sequence. | ||
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center protein; zoom 100; | center protein; zoom 100; | ||
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- | <text> | + | <text>Highlight Predicted Disordered Regions (84-246, 418-437, 592-634)</text> |
</jmolLink></jmol>) | </jmolLink></jmol>) |
Revision as of 13:46, 5 May 2025
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Zinc Fingers
Msn2 binds DNA via two C2H2 zinc finger domains located in the C-terminal region (residues 647-665 and 676-698).[4] These domains recognize the Stress Response Element (STRE) in the promoters of target genes.[1, 45] The AlphaFold model predicts these domains with high confidence (blue regions in the default view). Click the link to highlight these domains and the coordinating Zinc ions.
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The precise interaction with DNA likely involves specific residues within these fingers making contact with the STRE sequence.
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