9f65

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Current revision (05:39, 14 May 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9f65 is ON HOLD until Paper Publication
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==Crystal structure of thiol peroxidase mutant (C94A) in complex with Metro-P3* (H. pylori)==
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<StructureSection load='9f65' size='340' side='right'caption='[[9f65]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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Authors: Fiedler, M.K., Gong, R., Fuchs, S., Rox, K., Friedrich, V., Pfeiffer, D., Reinhardt, T., Mibus, C., Huber, M., Hess, C., Mejias-Luque, R., Gerhard, M., Groll, M., Sieber, S.A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9f65]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9F65 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9F65 FirstGlance]. <br>
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Description: Crystal structure of thiol peroxidase mutant (C94A) in complex with Metro-P3* (H. pylori)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1IAR:3-methyl-2-(prop-2-ynoxymethyl)imidazol-4-amine'>A1IAR</scene></td></tr>
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[[Category: Mejias-Luque, R]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9f65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9f65 OCA], [https://pdbe.org/9f65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9f65 RCSB], [https://www.ebi.ac.uk/pdbsum/9f65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9f65 ProSAT]</span></td></tr>
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[[Category: Gerhard, M]]
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</table>
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[[Category: Pfeiffer, D]]
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== Function ==
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[[Category: Rox, K]]
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[https://www.uniprot.org/uniprot/TPX_HELPY TPX_HELPY] Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.[HAMAP-Rule:MF_00269]<ref>PMID:9141476</ref>
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[[Category: Reinhardt, T]]
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== References ==
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[[Category: Sieber, S.A]]
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<references/>
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[[Category: Hess, C]]
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__TOC__
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[[Category: Fuchs, S]]
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</StructureSection>
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[[Category: Friedrich, V]]
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[[Category: Helicobacter pylori]]
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[[Category: Fiedler, M.K]]
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[[Category: Large Structures]]
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[[Category: Groll, M]]
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[[Category: Fiedler MK]]
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[[Category: Huber, M]]
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[[Category: Friedrich V]]
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[[Category: Gong, R]]
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[[Category: Fuchs S]]
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[[Category: Mibus, C]]
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[[Category: Gerhard M]]
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[[Category: Gong R]]
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[[Category: Groll M]]
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[[Category: Hess C]]
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[[Category: Huber M]]
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[[Category: Mejias-Luque R]]
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[[Category: Mibus C]]
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[[Category: Pfeiffer D]]
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[[Category: Reinhardt T]]
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[[Category: Rox K]]
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[[Category: Sieber SA]]

Current revision

Crystal structure of thiol peroxidase mutant (C94A) in complex with Metro-P3* (H. pylori)

PDB ID 9f65

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