9not

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Current revision (05:48, 14 May 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9not is ON HOLD until Paper Publication
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==Human sweet taste receptor (TAS1R2 + TAS1R3) from the sucralose dataset==
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<StructureSection load='9not' size='340' side='right'caption='[[9not]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9not]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NOT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NOT FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9not FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9not OCA], [https://pdbe.org/9not PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9not RCSB], [https://www.ebi.ac.uk/pdbsum/9not PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9not ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TS1R3_HUMAN TS1R3_HUMAN] Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.<ref>PMID:11917125</ref> <ref>PMID:12892531</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chang AN]]
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[[Category: Fitzpatrick AWP]]
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[[Category: Juen Z]]
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[[Category: Lu Z]]
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[[Category: Wang B]]
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[[Category: Yu R]]
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[[Category: Zuker CS]]

Current revision

Human sweet taste receptor (TAS1R2 + TAS1R3) from the sucralose dataset

PDB ID 9not

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OCA

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