9r2e

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "9r2e" [edit=sysop:move=sysop])
Current revision (05:51, 14 May 2025) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 9r2e is ON HOLD
+
==Structure of ARGX-121 Fab fragment in complex with the Fc fragment of IgA1==
-
 
+
<StructureSection load='9r2e' size='340' side='right'caption='[[9r2e]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
-
Authors: Pannecoucke, E., Voet, S., Deweirdt, L., Verbeiren, J., Gabriels, S., Provost, M., Freier, R., Koenig, J., Lammens, A., Silence, K.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[9r2e]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9R2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9R2E FirstGlance]. <br>
-
Description: Structure of ARGX-121 Fab fragment in complex with the Fc fragment of IgA1
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.54&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-
[[Category: Verbeiren, J]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9r2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9r2e OCA], [https://pdbe.org/9r2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9r2e RCSB], [https://www.ebi.ac.uk/pdbsum/9r2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9r2e ProSAT]</span></td></tr>
-
[[Category: Voet, S]]
+
</table>
-
[[Category: Silence, K]]
+
== Disease ==
-
[[Category: Gabriels, S]]
+
[https://www.uniprot.org/uniprot/IGHA1_HUMAN IGHA1_HUMAN] Note=A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.
-
[[Category: Provost, M]]
+
== Function ==
-
[[Category: Pannecoucke, E]]
+
[https://www.uniprot.org/uniprot/IGHA1_HUMAN IGHA1_HUMAN] Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
-
[[Category: Koenig, J]]
+
__TOC__
-
[[Category: Lammens, A]]
+
</StructureSection>
-
[[Category: Freier, R]]
+
[[Category: Homo sapiens]]
-
[[Category: Deweirdt, L]]
+
[[Category: Large Structures]]
 +
[[Category: Deweirdt L]]
 +
[[Category: Freier R]]
 +
[[Category: Gabriels S]]
 +
[[Category: Koenig J]]
 +
[[Category: Lammens A]]
 +
[[Category: Pannecoucke E]]
 +
[[Category: Provost M]]
 +
[[Category: Silence K]]
 +
[[Category: Verbeiren J]]
 +
[[Category: Voet S]]

Current revision

Structure of ARGX-121 Fab fragment in complex with the Fc fragment of IgA1

PDB ID 9r2e

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/9r2e"
Personal tools