8ziv

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Current revision (08:52, 21 May 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8ziv is ON HOLD until Paper Publication
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==wtEP-trypsinogen in Tryp-1==
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<StructureSection load='8ziv' size='340' side='right'caption='[[8ziv]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
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Authors: Song, Q.Y., Ding, Z.Y., Huang, H.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8ziv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZIV FirstGlance]. <br>
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Description: wtEP-trypsinogen in Tryp-1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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[[Category: Huang, H.J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ziv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ziv OCA], [https://pdbe.org/8ziv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ziv RCSB], [https://www.ebi.ac.uk/pdbsum/8ziv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ziv ProSAT]</span></td></tr>
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[[Category: Ding, Z.Y]]
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</table>
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[[Category: Song, Q.Y]]
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== Disease ==
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[https://www.uniprot.org/uniprot/ENTK_HUMAN ENTK_HUMAN] Congenital enteropathy due to enteropeptidase deficiency. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/ENTK_HUMAN ENTK_HUMAN] Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Ding ZY]]
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[[Category: Huang HJ]]
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[[Category: Song QY]]

Current revision

wtEP-trypsinogen in Tryp-1

PDB ID 8ziv

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