8zeu

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Current revision (05:23, 28 May 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8zeu is ON HOLD
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==CryoEM structure of GR2002-F(ab')2: TSLP complex==
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<StructureSection load='8zeu' size='340' side='right'caption='[[8zeu]], [[Resolution|resolution]] 3.39&Aring;' scene=''>
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Authors: Zhigang, L., Junjie, H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8zeu]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZEU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZEU FirstGlance]. <br>
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Description: CryoEM structure of GR2002-F(ab'')2: TSLP complex
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.39&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zeu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zeu OCA], [https://pdbe.org/8zeu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zeu RCSB], [https://www.ebi.ac.uk/pdbsum/8zeu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zeu ProSAT]</span></td></tr>
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[[Category: Junjie, H]]
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</table>
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[[Category: Zhigang, L]]
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== Function ==
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[https://www.uniprot.org/uniprot/TSLP_HUMAN TSLP_HUMAN] Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.<ref>PMID:11418668</ref> <ref>PMID:11480573</ref> <ref>PMID:17242164</ref> Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin.<ref>PMID:24850429</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Junjie H]]
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[[Category: Zhigang L]]

Current revision

CryoEM structure of GR2002-F(ab')2: TSLP complex

PDB ID 8zeu

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