9fe2

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Current revision (05:30, 28 May 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9fe2 is ON HOLD until Paper Publication
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==Crystallographic structure of AcrB V612W with bound minocycline==
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<StructureSection load='9fe2' size='340' side='right'caption='[[9fe2]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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Authors: Lazarova, M., Pos, K.M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9fe2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FE2 FirstGlance]. <br>
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Description: Crystallographic structure of AcrB V612W with bound minocycline
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MIY:(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE'>MIY</scene></td></tr>
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[[Category: Pos, K.M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9fe2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fe2 OCA], [https://pdbe.org/9fe2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fe2 RCSB], [https://www.ebi.ac.uk/pdbsum/9fe2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fe2 ProSAT]</span></td></tr>
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[[Category: Lazarova, M]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Synthetic construct]]
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[[Category: Lazarova M]]
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[[Category: Pos KM]]

Current revision

Crystallographic structure of AcrB V612W with bound minocycline

PDB ID 9fe2

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