Epoxide hydrolase 3D structures
From Proteopedia
(Difference between revisions)
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**[[1qo7]], [[3g02]] – AnEH (mutant) – ''Aspergillus niger''<br /> | **[[1qo7]], [[3g02]] – AnEH (mutant) – ''Aspergillus niger''<br /> | ||
**[[6ix4]] – AuEH – ''Aspergillus usamii''<br /> | **[[6ix4]] – AuEH – ''Aspergillus usamii''<br /> | ||
| - | **[[6ix2]] – | + | **[[6ix2]] – AuEH (mutant) <br /> |
**[[4i19]], [[4qa9]], [[5f4z]] – EH – ''Streptomyces carzinostaticus''<br /> | **[[4i19]], [[4qa9]], [[5f4z]] – EH – ''Streptomyces carzinostaticus''<br /> | ||
**[[5cxo]], [[6unw]] – EH – ''Streptomyces albus''<br /> | **[[5cxo]], [[6unw]] – EH – ''Streptomyces albus''<br /> | ||
**[[5nfq]], [[5ng7]] – meEH – metagenome<br /> | **[[5nfq]], [[5ng7]] – meEH – metagenome<br /> | ||
**[[7cg2]], [[7cg6]] – EH (mutant) – ''Vigna radiata''<br /> | **[[7cg2]], [[7cg6]] – EH (mutant) – ''Vigna radiata''<br /> | ||
| + | **[[8wbk]], [[8wbl]], [[8wbp]], [[8wnh]] – RoEH – ''Rhodococcus opacus''<br /> | ||
| + | **[[8wbm]], [[8wbn]], [[8wbo]] – RoEH (mutant) <br /> | ||
| + | **[[8hgu]] – EH – ''Bosea''<br /> | ||
| + | **[[8hm5]] – EH – ''Caballeronia sordidicola''<br /> | ||
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| + | *Epoxide hydrolase 2 | ||
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| + | **[[8jy1]] – EH2 – mango<br /> | ||
*Soluble epoxide hydrolase or bifunctional epoxide hydrolase 2 | *Soluble epoxide hydrolase or bifunctional epoxide hydrolase 2 | ||
| - | **[[1s8o]], [[3i1y]], [[3i28]], [[3koo]], [[5ahx]], [[5fp0]] – hSEH – human<br /> | + | **[[1s8o]], [[3i1y]], [[3i28]], [[3koo]], [[5ahx]], [[5fp0]], [[8qvk]], [[8qvm]], [[8qwg]] – hSEH – human<br /> |
| + | **[[9exm]] – hSEH – Cryo EM<br /> | ||
**[[6i5e]] – hSEH C terminal<br /> | **[[6i5e]] – hSEH C terminal<br /> | ||
**[[1cqz]] – mSEH – mouse<br /> | **[[1cqz]] – mSEH – mouse<br /> | ||
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**[[3rga]] – SlEH + oxazolidinone inhibitor – ''Streptomyces lasaliensis''<br /> | **[[3rga]] – SlEH + oxazolidinone inhibitor – ''Streptomyces lasaliensis''<br /> | ||
**[[4rzm]] – SlEH + lasalocid A<br /> | **[[4rzm]] – SlEH + lasalocid A<br /> | ||
| - | **[[6n3k]] – | + | **[[6n3k]] – TrEH + urea derivative inhibitor – ''Trichoderma reesei''<br /> |
| - | **[[6n3z]] – | + | **[[6n3z]] – TrEH + benzamide derivative inhibitor <br /> |
| - | **[[6n5h]] – | + | **[[6n5h]] – TrEH + benzoate derivative inhibitor <br /> |
| - | **[[6n5f]] – | + | **[[6n5f]] – TrEH + nonanamide derivative inhibitor <br /> |
| - | **[[6n5g]] – | + | **[[6n5g]] – TrEH + piperidine derivative inhibitor<br /> |
| - | **[[2zjf]] – | + | **[[2zjf]] – MtEH + inhibitor<br /> |
| + | |||
| + | *Epoxide hydrolase complex with product | ||
| + | |||
| + | **[[8wbq]] – RoEH + tartarate<br /> | ||
*Soluble epoxide hydrolase complex with inhibitor | *Soluble epoxide hydrolase complex with inhibitor | ||
| - | **[[1vj5]], [[1zd2]], [[1zd3]], [[1zd4]], [[1zd5]], [[3wk4]], [[4c4x]], [[4c4y]], [[4c4z]], [[5ai5]], [[5akz]], [[5ali]], [[6aum]], [[6fr2]], [[6hgx]] – hSEH + urea derivative inhibitor<br /> | + | **[[1vj5]], [[1zd2]], [[1zd3]], [[1zd4]], [[1zd5]], [[3wk4]], [[4c4x]], [[4c4y]], [[4c4z]], [[5ai5]], [[5akz]], [[5ali]], [[6aum]], [[6fr2]], [[6hgx]], [[8qvf]], [[9f1a]] – hSEH + urea derivative inhibitor<br /> |
**[[3otq]], [[3wk7]], [[4y2j]], [[4y2s]], [[4y2v]], [[5ak4]], [[5akh]], [[5aki]], [[5alk]], [[5alq]], [[5alv]], [[5aly]] – hSEH + pyrazole inhibitor<br /> | **[[3otq]], [[3wk7]], [[4y2j]], [[4y2s]], [[4y2v]], [[5ak4]], [[5akh]], [[5aki]], [[5alk]], [[5alq]], [[5alv]], [[5aly]] – hSEH + pyrazole inhibitor<br /> | ||
| - | **[[5akj]], [[5alf]], [[5als]] – hSEH + imidazole inhibitor<br /> | + | **[[5akj]], [[5alf]], [[5als]], [[8qwi]] – hSEH + imidazole inhibitor<br /> |
**[[5akk]], [[5ald]], [[5aln]], [[5alo]], [[5alw]], [[5am4]] – hSEH + indolone inhibitor<br /> | **[[5akk]], [[5ald]], [[5aln]], [[5alo]], [[5alw]], [[5am4]] – hSEH + indolone inhibitor<br /> | ||
**[[5akx]], [[5aky]] – hSEH + indazole inhibitor<br /> | **[[5akx]], [[5aky]] – hSEH + indazole inhibitor<br /> | ||
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**[[4x6x]], [[4x6y]] – hSEH catalytic domain + cyclopropane inhibitor<br /> | **[[4x6x]], [[4x6y]] – hSEH catalytic domain + cyclopropane inhibitor<br /> | ||
**[[7a7g]] – hSEH catalytic domain + inhibitor<br /> | **[[7a7g]] – hSEH catalytic domain + inhibitor<br /> | ||
| - | **[[4hai]], [[3wka]], [[4ocz]], [[4od0]], [[5ake]], [[5alh]], [[5am1]] – hSEH + piperidine derivative inhibitor<br /> | + | **[[4hai]], [[3wka]], [[4ocz]], [[4od0]], [[5ake]], [[5alh]], [[5am1]], [[9kpi]] – hSEH + piperidine derivative inhibitor<br /> |
**[[4y2p]], [[4y2q]], [[5ai4]], [[5ak5]], [[5ak6]], [[5alt]], [[5am5]] – hSEH + pyridine derivative inhibitor<br /> | **[[4y2p]], [[4y2q]], [[5ai4]], [[5ak5]], [[5ak6]], [[5alt]], [[5am5]] – hSEH + pyridine derivative inhibitor<br /> | ||
**[[4y2r]] – hSEH + piperazine derivative inhibitor<br /> | **[[4y2r]] – hSEH + piperazine derivative inhibitor<br /> | ||
| - | **[[5akl]], [[5alm]], [[5am0]] – hSEH + pyrrolidine derivative inhibitor<br /> | + | **[[5akl]], [[5alm]], [[5am0]], [[8qmz]], [[8qn0]], [[8qvg]] – hSEH + pyrrolidine derivative inhibitor<br /> |
**[[6yl4]] – hSEH + benzamide derivative inhibitor <br /> | **[[6yl4]] – hSEH + benzamide derivative inhibitor <br /> | ||
**[[4y2t]], [[5aib]] – hSEH + benzyloxy derivative inhibitor<br /> | **[[4y2t]], [[5aib]] – hSEH + benzyloxy derivative inhibitor<br /> | ||
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**[[6hgv]] – hSEH + talinonol<br /> | **[[6hgv]] – hSEH + talinonol<br /> | ||
**[[7eba]] – hSEH + kurarinone<br /> | **[[7eba]] – hSEH + kurarinone<br /> | ||
| + | **[[8qzd]] – hSEH + epoxykinin<br /> | ||
**[[5ai0]] – hSEH + phenyl oxadiazolamine inhibitor<br /> | **[[5ai0]] – hSEH + phenyl oxadiazolamine inhibitor<br /> | ||
**[[5ai9]] – hSEH + phenol derivative inhibitor<br /> | **[[5ai9]] – hSEH + phenol derivative inhibitor<br /> | ||
| - | **[[5aia]], [[5mwa]] – hSEH + benzoate derivative inhibitor<br /> | + | **[[5aia]], [[5mwa]], [[8qvh]] – hSEH + benzoate derivative inhibitor<br /> |
**[[5ak3]] – hSEH + indan-amine derivative inhibitor<br /> | **[[5ak3]] – hSEH + indan-amine derivative inhibitor<br /> | ||
**[[6hgw]] – hSEH + ethanamine derivative inhibitor<br /> | **[[6hgw]] – hSEH + ethanamine derivative inhibitor<br /> | ||
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**[[7xee]] – ReLEH (mutant) + ethanamide derivative<br /> | **[[7xee]] – ReLEH (mutant) + ethanamide derivative<br /> | ||
**[[7xef]] – ReLEH (mutant) + pyrrolidine derivative<br /> | **[[7xef]] – ReLEH (mutant) + pyrrolidine derivative<br /> | ||
| - | **[[5aif]], [[5aih]], [[5aii]] – mlLEH – metagenomic library<br /> | + | **[[5aif]], [[5aih]], [[5aii]], [[8agm]], [[8agn]], [[8agp]], [[8ags]] – mlLEH – metagenomic library<br /> |
**[[5aig]] – mlLEH + valpromide <br /> | **[[5aig]] – mlLEH + valpromide <br /> | ||
Current revision
3D Structures of epoxide hydrolase
Updated on 01-June-2025
