9g74

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Current revision (08:26, 4 June 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9g74 is ON HOLD until Paper Publication
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==Mouse mitochondrial DNA polymerase gamma ternary complex in replication conformer==
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<StructureSection load='9g74' size='340' side='right'caption='[[9g74]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9g74]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9G74 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9G74 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DCP:2-DEOXYCYTIDINE-5-TRIPHOSPHATE'>DCP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9g74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9g74 OCA], [https://pdbe.org/9g74 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9g74 RCSB], [https://www.ebi.ac.uk/pdbsum/9g74 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9g74 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q75WC0_MOUSE Q75WC0_MOUSE] Catalytic subunit of DNA polymerase gamma solely responsible for replication of mitochondrial DNA (mtDNA). Replicates both heavy and light strands of the circular mtDNA genome using a single-stranded DNA template, RNA primers and the four deoxyribonucleoside triphosphates as substrates.[PIRNR:PIRNR000797]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Synthetic construct]]
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[[Category: Falkenberg M]]
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[[Category: Valenzuela S]]

Current revision

Mouse mitochondrial DNA polymerase gamma ternary complex in replication conformer

PDB ID 9g74

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