9msx
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Candida albicans Hsp90 nucleotide binding domain in complex with TAS116== | |
| - | + | <StructureSection load='9msx' size='340' side='right'caption='[[9msx]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9msx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MSX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1BPC:3-ethyl-4-[4-[4-(1-methylpyrazol-4-yl)imidazol-1-yl]-3-propan-2-yl-pyrazolo[3,4-b]pyridin-1-yl]benzamide'>A1BPC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9msx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9msx OCA], [https://pdbe.org/9msx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9msx RCSB], [https://www.ebi.ac.uk/pdbsum/9msx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9msx ProSAT]</span></td></tr> |
| - | [[Category: Kowalewski | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HSP90_CANAL HSP90_CANAL] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Candida albicans]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kowalewski ME]] | ||
| + | [[Category: Redinbo MR]] | ||
Current revision
Candida albicans Hsp90 nucleotide binding domain in complex with TAS116
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