7r89

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====
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==The structure of human ABCG5/ABCG8 purified from yeast==
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<StructureSection load='7r89' size='340' side='right'caption='[[7r89]]' scene=''>
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<StructureSection load='7r89' size='340' side='right'caption='[[7r89]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7r89]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R89 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r89 OCA], [https://pdbe.org/7r89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r89 RCSB], [https://www.ebi.ac.uk/pdbsum/7r89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r89 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ERG:ERGOSTEROL'>ERG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r89 OCA], [https://pdbe.org/7r89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r89 RCSB], [https://www.ebi.ac.uk/pdbsum/7r89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r89 ProSAT]</span></td></tr>
</table>
</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/ABCG5_HUMAN ABCG5_HUMAN] Sitosterolemia. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/ABCG5_HUMAN ABCG5_HUMAN] Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.
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==See Also==
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*[[ABC transporter 3D structures|ABC transporter 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Mus musculus]]
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[[Category: Li X]]
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[[Category: Long T]]
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[[Category: Sun Y]]

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The structure of human ABCG5/ABCG8 purified from yeast

PDB ID 7r89

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