User:Giulia Mencarini Reinhardt/Sandbox 1
From Proteopedia
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==ACE2 (angiotensin-converting enzyme 2)== | ==ACE2 (angiotensin-converting enzyme 2)== | ||
<StructureSection load='1R42' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1R42' size='340' side='right' caption='Caption for this structure' scene=''> | ||
| - | + | (TRADUZIR)A enzima conversora de angiotensina 2 (ACE2) é uma importante enzima do sistema renina-angiotensina-aldosterona (SRAA). Ela pode ser encontrada em diversos tecidos, seja ancorada à membrana celular (mACE2), como uma proteína transmembrana, ou em uma forma solúvel, chamada sACE2. | |
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| + | Outra função da enzima conversora de angiotensina 2 é servir como receptor para alguns vírus, incluindo o SARS-CoV-2, responsável pela pandemia de COVID-19 em 2020. Essa ligação ao receptor e a entrada na célula ocorrem pela ligação da subunidade S1 da proteína Spike (S) do vírus à ACE2. [1] | ||
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
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== Function == | == Function == | ||
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== Disease == | == Disease == | ||
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== Relevance == | == Relevance == | ||
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== Structural highlights == | == Structural highlights == | ||
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
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== References == | == References == | ||
<references/> | <references/> | ||
| + | [1] Beyerstedt S, Casaro EB, Rangel ÉB. COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection. Eur J Clin Microbiol Infect Dis. 2021 May;40(5):905-919. doi: 10.1007/s10096-020-04138-6. Epub 2021 Jan 3. PMID: 33389262; PMCID: PMC7778857. | ||
Revision as of 17:43, 8 June 2025
ACE2 (angiotensin-converting enzyme 2)
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
[1] Beyerstedt S, Casaro EB, Rangel ÉB. COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection. Eur J Clin Microbiol Infect Dis. 2021 May;40(5):905-919. doi: 10.1007/s10096-020-04138-6. Epub 2021 Jan 3. PMID: 33389262; PMCID: PMC7778857.
