This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1w33

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1w33.gif|left|200px]]
[[Image:1w33.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1w33 |SIZE=350|CAPTION= <scene name='initialview01'>1w33</scene>, resolution 2.7&Aring;
+
The line below this paragraph, containing "STRUCTURE_1w33", creates the "Structure Box" on the page.
-
|SITE= <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene>
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1w33| PDB=1w33 | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w33 OCA], [http://www.ebi.ac.uk/pdbsum/1w33 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1w33 RCSB]</span>
+
-
}}
+
'''BBCRASP-1 FROM BORRELIA BURGDORFERI'''
'''BBCRASP-1 FROM BORRELIA BURGDORFERI'''
Line 37: Line 34:
[[Category: Wallich, R.]]
[[Category: Wallich, R.]]
[[Category: Zipfel, P.]]
[[Category: Zipfel, P.]]
-
[[Category: complement regulator acquiring surface protein]]
+
[[Category: Complement regulator acquiring surface protein]]
-
[[Category: factor h binding]]
+
[[Category: Factor h binding]]
-
[[Category: lyme borreliosis]]
+
[[Category: Lyme borreliosis]]
-
[[Category: membrane protein]]
+
[[Category: Membrane protein]]
-
[[Category: tick]]
+
[[Category: Tick]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 13:05:15 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:30:28 2008''
+

Revision as of 10:05, 3 May 2008

Image:1w33.gif


PDB ID 1w33

Drag the structure with the mouse to rotate
1w33, resolution 2.70Å ()
Ligands:
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



BBCRASP-1 FROM BORRELIA BURGDORFERI


Overview

Borrelia burgdorferi, a spirochete transmitted to human hosts during feeding of infected Ixodes ticks, is the causative agent of Lyme disease. Serum-resistant B. burgdorferi strains cause a chronic, multisystemic form of the disease and bind complement factor H (FH) and FH-like protein 1 (FHL-1) on the spirochete surface. Here we report the atomic structure for the key FHL-1- and FH-binding protein BbCRASP-1 and reveal a homodimer that presents a novel target for drug design.

About this Structure

1W33 is a Single protein structure of sequence from Borrelia burgdorferi. Full crystallographic information is available from OCA.

Reference

A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia burgdorferi., Cordes FS, Roversi P, Kraiczy P, Simon MM, Brade V, Jahraus O, Wallis R, Skerka C, Zipfel PF, Wallich R, Lea SM, Nat Struct Mol Biol. 2005 Mar;12(3):276-7. Epub 2005 Feb 13. PMID:15711564 Page seeded by OCA on Sat May 3 13:05:15 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1w33"
Personal tools