7wgr

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Current revision (11:23, 18 June 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7wgr is ON HOLD until Paper Publication
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==Cryo-electron microscopic structure of the 2-oxoglutarate dehydrogenase (E1) component of the human alpha-ketoglutarate (2-oxoglutarate) dehydrogenase complex==
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<StructureSection load='7wgr' size='340' side='right'caption='[[7wgr]], [[Resolution|resolution]] 2.92&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7wgr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WGR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WGR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.92&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wgr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wgr OCA], [https://pdbe.org/7wgr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wgr RCSB], [https://www.ebi.ac.uk/pdbsum/7wgr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wgr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ODO1_HUMAN ODO1_HUMAN] The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
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Authors: Yu, X., Yang, W., Zhong, Y.H., Ma, X.M., Gao, Y.Z.
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==See Also==
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*[[2-oxoglutarate dehydrogenase 3D structures|2-oxoglutarate dehydrogenase 3D structures]]
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Description: Cryo-electron microscopic structure of the 2-oxoglutarate dehydrogenase (E1) component of the human alpha-ketoglutarate (2-oxoglutarate) dehydrogenase complex
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Yu, X]]
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[[Category: Homo sapiens]]
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[[Category: Ma, X.M]]
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[[Category: Large Structures]]
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[[Category: Zhong, Y.H]]
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[[Category: Gao YZ]]
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[[Category: Yang, W]]
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[[Category: Ma XM]]
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[[Category: Gao, Y.Z]]
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[[Category: Yang W]]
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[[Category: Yu X]]
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[[Category: Zhong YH]]

Current revision

Cryo-electron microscopic structure of the 2-oxoglutarate dehydrogenase (E1) component of the human alpha-ketoglutarate (2-oxoglutarate) dehydrogenase complex

PDB ID 7wgr

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