9c82
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human ULK1C:PI3KC3-C1 supercomplex== | |
| - | + | <StructureSection load='9c82' size='340' side='right'caption='[[9c82]], [[Resolution|resolution]] 6.84Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9c82]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9C82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9C82 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.84Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9c82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9c82 OCA], [https://pdbe.org/9c82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9c82 RCSB], [https://www.ebi.ac.uk/pdbsum/9c82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9c82 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Chen | + | == Function == |
| + | [https://www.uniprot.org/uniprot/PI3R4_HUMAN PI3R4_HUMAN] Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123).<ref>PMID:20643123</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen M]] | ||
| + | [[Category: Hurley JH]] | ||
Current revision
Structure of human ULK1C:PI3KC3-C1 supercomplex
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