1w3w

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1w3w.gif|left|200px]]
[[Image:1w3w.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1w3w |SIZE=350|CAPTION= <scene name='initialview01'>1w3w</scene>, resolution 1.99&Aring;
+
The line below this paragraph, containing "STRUCTURE_1w3w", creates the "Structure Box" on the page.
-
|SITE= <scene name='pdbsite=AC1:Ca+Binding+Site+For+Chain+A'>AC1</scene>
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1w3w| PDB=1w3w | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w3w OCA], [http://www.ebi.ac.uk/pdbsum/1w3w PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1w3w RCSB]</span>
+
-
}}
+
'''THE 2.1 ANGSTROEM RESOLUTION STRUCTURE OF ANNEXIN A8'''
'''THE 2.1 ANGSTROEM RESOLUTION STRUCTURE OF ANNEXIN A8'''
Line 29: Line 26:
[[Category: Rety, S.]]
[[Category: Rety, S.]]
[[Category: Santos, J Sopkova-De Oliveira.]]
[[Category: Santos, J Sopkova-De Oliveira.]]
-
[[Category: annexin family]]
+
[[Category: Annexin family]]
-
[[Category: calcium and phospholipid binding protein]]
+
[[Category: Calcium and phospholipid binding protein]]
-
[[Category: coagulation]]
+
[[Category: Coagulation]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 13:07:16 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:30:50 2008''
+

Revision as of 10:07, 3 May 2008

Image:1w3w.gif

Template:STRUCTURE 1w3w

THE 2.1 ANGSTROEM RESOLUTION STRUCTURE OF ANNEXIN A8


Overview

Annexin A8 is a relatively infrequent and poorly studied member of this large family of calcium-binding and membrane-binding proteins. It is, however, associated with a specific disease, acute promyelocytic leukemia. We have solved its three-dimensional structure, which includes a moderately long and intact N terminus. The structure is closest to that of annexin A3 and highlights several important regions of inherent flexibility in the annexin molecule. The N terminus resembles that of annexin A3, as it lies along the concave surface of the molecule and inserts partially into the hydrophilic channel in its centre. Since both annexins A3 and A8 are expressed in promyelocytic cells during their differentiation, the similarity in their structures might suggest a functional relationship.

About this Structure

1W3W is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The crystal structure of annexin A8 is similar to that of annexin A3., Rety S, Sopkova-de Oliveira Santos J, Dreyfuss L, Blondeau K, Hofbauerova K, Raguenes-Nicol C, Kerboeuf D, Renouard M, Russo-Marie F, Lewit-Bentley A, J Mol Biol. 2005 Feb 4;345(5):1131-9. Epub 2004 Dec 8. PMID:15644210 Page seeded by OCA on Sat May 3 13:07:16 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1w3w"
Personal tools