9foi
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human KCTD1== | |
| - | + | <StructureSection load='9foi' size='340' side='right'caption='[[9foi]], [[Resolution|resolution]] 2.71Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9foi]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FOI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FOI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.71Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9foi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9foi OCA], [https://pdbe.org/9foi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9foi RCSB], [https://www.ebi.ac.uk/pdbsum/9foi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9foi ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/KCTD1_HUMAN KCTD1_HUMAN] Scalp-ear-nipple syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KCTD1_HUMAN KCTD1_HUMAN] May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.<ref>PMID:18358072</ref> <ref>PMID:19115315</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Borkowska O]] | ||
| + | [[Category: Bufton JC]] | ||
| + | [[Category: Bullock AN]] | ||
| + | [[Category: Burgess-Brown NA]] | ||
| + | [[Category: Hunt AE]] | ||
| + | [[Category: Manning CE]] | ||
| + | [[Category: Pike ACW]] | ||
| + | [[Category: Pinkas DM]] | ||
| + | [[Category: Richardson W]] | ||
| + | [[Category: Shrestha L]] | ||
Current revision
Structure of human KCTD1
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Categories: Homo sapiens | Large Structures | Borkowska O | Bufton JC | Bullock AN | Burgess-Brown NA | Hunt AE | Manning CE | Pike ACW | Pinkas DM | Richardson W | Shrestha L
