9hc3
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Apo-state structure of the human metabotropic glutamate receptor 5 transmembrane domain freeze-trapped after light activation of photoswitchable ligand alloswitch-1== | |
| - | + | <StructureSection load='9hc3' size='340' side='right'caption='[[9hc3]], [[Resolution|resolution]] 2.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9hc3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HC3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HC3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hc3 OCA], [https://pdbe.org/9hc3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hc3 RCSB], [https://www.ebi.ac.uk/pdbsum/9hc3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hc3 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Cheng | + | [https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref> [https://www.uniprot.org/uniprot/GRM5_HUMAN GRM5_HUMAN] Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia virus T4]] |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Mason | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Bertrand Q]] |
| - | [[Category: | + | [[Category: Cheng R]] |
| - | [[Category: | + | [[Category: Dworkowski F]] |
| - | [[Category: | + | [[Category: Glover H]] |
| - | [[Category: | + | [[Category: Hatton C]] |
| + | [[Category: Hennig M]] | ||
| + | [[Category: Kepa M]] | ||
| + | [[Category: Kondo Y]] | ||
| + | [[Category: Mason T]] | ||
| + | [[Category: Mehrabi P]] | ||
| + | [[Category: Sarma S]] | ||
| + | [[Category: Seidel HP]] | ||
| + | [[Category: Standfuss J]] | ||
| + | [[Category: Stierli F]] | ||
| + | [[Category: Tellkamp F]] | ||
| + | [[Category: Trabuco M]] | ||
Current revision
Apo-state structure of the human metabotropic glutamate receptor 5 transmembrane domain freeze-trapped after light activation of photoswitchable ligand alloswitch-1
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Categories: Escherichia virus T4 | Homo sapiens | Large Structures | Bertrand Q | Cheng R | Dworkowski F | Glover H | Hatton C | Hennig M | Kepa M | Kondo Y | Mason T | Mehrabi P | Sarma S | Seidel HP | Standfuss J | Stierli F | Tellkamp F | Trabuco M
