9hjs
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human geranylgeranyl diphosphate synthase mutant R235C== | |
| - | + | <StructureSection load='9hjs' size='340' side='right'caption='[[9hjs]], [[Resolution|resolution]] 2.51Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9hjs]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HJS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HJS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.51Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GRG:GERANYLGERANYL+DIPHOSPHATE'>GRG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hjs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hjs OCA], [https://pdbe.org/9hjs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hjs RCSB], [https://www.ebi.ac.uk/pdbsum/9hjs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hjs ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GGPPS_HUMAN GGPPS_HUMAN] Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Giladi M]] | ||
| + | [[Category: Haitin Y]] | ||
| + | [[Category: Yehia R]] | ||
Current revision
Crystal structure of human geranylgeranyl diphosphate synthase mutant R235C
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