9kzc
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the LGI1 LRR-LGI1 EPTP-ADAM22 ECD complex== | |
| - | + | <StructureSection load='9kzc' size='340' side='right'caption='[[9kzc]], [[Resolution|resolution]] 2.78Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9kzc]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KZC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.78Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kzc OCA], [https://pdbe.org/9kzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kzc RCSB], [https://www.ebi.ac.uk/pdbsum/9kzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kzc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ADA22_HUMAN ADA22_HUMAN] Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.<ref>PMID:12589811</ref> <ref>PMID:15882968</ref> <ref>PMID:16385342</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fukai S]] | ||
| + | [[Category: Kubota M]] | ||
| + | [[Category: Mitsumori A]] | ||
| + | [[Category: Okatsu K]] | ||
| + | [[Category: Yamagata A]] | ||
| + | [[Category: Yamaguchi T]] | ||
Current revision
Cryo-EM structure of the LGI1 LRR-LGI1 EPTP-ADAM22 ECD complex
| |||||||||||
