9nqd

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m (Protected "9nqd" [edit=sysop:move=sysop])
Current revision (06:23, 25 June 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9nqd is ON HOLD until Paper Publication
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==Structural Basis of Pseudomonas FapC Biofilm-Forming Functional Amyloid Formation==
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<StructureSection load='9nqd' size='340' side='right'caption='[[9nqd]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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Authors: Hansen, K.H., Golcuk, M., Byeon, C.B., Plechinger, E.B., Conway, J.F., Andreasen, M., Gur, M., Akbey, U.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9nqd]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_fluorescens Pseudomonas fluorescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NQD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NQD FirstGlance]. <br>
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Description: Structural Basis of Pseudomonas FapC Biofilm-Forming Functional Amyloid Formation
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9nqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9nqd OCA], [https://pdbe.org/9nqd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9nqd RCSB], [https://www.ebi.ac.uk/pdbsum/9nqd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9nqd ProSAT]</span></td></tr>
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[[Category: Conway, J.F]]
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</table>
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[[Category: Plechinger, E.B]]
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== Function ==
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[[Category: Byeon, C.B]]
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[https://www.uniprot.org/uniprot/FAPC_PSEFL FAPC_PSEFL] The major functional amyloid subunit in this bacterium (PubMed:20572935, PubMed:23504942). Intrinsically disordered in its monomeric state (PubMed:37162737, PubMed:38349812). Upon overexpression of the endogenous six-gene locus (fapA-fapF) in situ, cells form large clumps during liquid growth, make large amounts of biofilm and produce amyloid fibrils (PubMed:23504942, PubMed:26500638). Expression of the 6 gene operon in E.coli strain BL21(DE3) induces flocculation and biofilm formation with copious extracellular fibrils (PubMed:20572935, PubMed:28811582).<ref>PMID:20572935</ref> <ref>PMID:23504942</ref> <ref>PMID:26500638</ref> <ref>PMID:28811582</ref> <ref>PMID:37162737</ref> <ref>PMID:38349812</ref>
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[[Category: Hansen, K.H]]
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== References ==
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[[Category: Gur, M]]
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<references/>
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[[Category: Akbey, U]]
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__TOC__
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[[Category: Andreasen, M]]
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</StructureSection>
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[[Category: Golcuk, M]]
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[[Category: Large Structures]]
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[[Category: Pseudomonas fluorescens]]
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[[Category: Akbey U]]
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[[Category: Andreasen M]]
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[[Category: Byeon CB]]
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[[Category: Conway JF]]
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[[Category: Golcuk M]]
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[[Category: Gur M]]
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[[Category: Hansen KH]]
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[[Category: Plechinger EB]]

Current revision

Structural Basis of Pseudomonas FapC Biofilm-Forming Functional Amyloid Formation

PDB ID 9nqd

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