9kr7

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Current revision (07:23, 25 June 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9kr7 is ON HOLD until Paper Publication
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==human creatine transporter==
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<StructureSection load='9kr7' size='340' side='right'caption='[[9kr7]], [[Resolution|resolution]] 3.29&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9kr7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KR7 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.29&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kr7 OCA], [https://pdbe.org/9kr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kr7 RCSB], [https://www.ebi.ac.uk/pdbsum/9kr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kr7 ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/SC6A8_HUMAN SC6A8_HUMAN] X-linked creatine transporter deficiency. The disease is caused by variants affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/SC6A8_HUMAN SC6A8_HUMAN] Creatine:sodium symporter which mediates the uptake of creatine (PubMed:17465020, PubMed:22644605, PubMed:25861866, PubMed:7945388, PubMed:7953292, PubMed:9882430). Plays an important role in supplying creatine to the brain via the blood-brain barrier (By similarity).[UniProtKB:Q8VBW1]<ref>PMID:17465020</ref> <ref>PMID:22644605</ref> <ref>PMID:25861866</ref> <ref>PMID:7945388</ref> <ref>PMID:7953292</ref> <ref>PMID:9882430</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chen JH]]
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[[Category: Ge JP]]
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[[Category: Yu J]]

Current revision

human creatine transporter

PDB ID 9kr7

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OCA

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