9cv1

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m (Protected "9cv1" [edit=sysop:move=sysop])
Current revision (05:23, 3 July 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9cv1 is ON HOLD until Paper Publication
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==Crystal structure of the metallo-beta-lactamase VIM-15 with L-captopril==
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<StructureSection load='9cv1' size='340' side='right'caption='[[9cv1]], [[Resolution|resolution]] 1.29&Aring;' scene=''>
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Authors: Silwal, S.B., Nix, J.C., Page, R.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9cv1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CV1 FirstGlance]. <br>
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Description: Crystal structure of the metallo-beta-lactamase VIM-15 with L-captopril
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.29&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=X8Z:L-CAPTOPRIL'>X8Z</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Page, R.C]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9cv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9cv1 OCA], [https://pdbe.org/9cv1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9cv1 RCSB], [https://www.ebi.ac.uk/pdbsum/9cv1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cv1 ProSAT]</span></td></tr>
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[[Category: Silwal, S.B]]
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</table>
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[[Category: Nix, J.C]]
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== Function ==
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[https://www.uniprot.org/uniprot/B4YAJ6_PSEAI B4YAJ6_PSEAI] Class B beta-lactamase which confers resistance to the beta-lactam antibiotics, including penicillins, cephalosporins and carbapenems. Acts via hydrolysis of the beta-lactam ring. Has penicillin-, cephalosporin- and carbapenem-hydrolyzing activities.[ARBA:ARBA00055160]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Nix JC]]
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[[Category: Page RC]]
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[[Category: Silwal SB]]

Current revision

Crystal structure of the metallo-beta-lactamase VIM-15 with L-captopril

PDB ID 9cv1

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