6a91

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Current revision (05:43, 3 July 2025) (edit) (undo)
 
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<SX load='6a91' size='340' side='right' viewer='molstar' caption='[[6a91]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<SX load='6a91' size='340' side='right' viewer='molstar' caption='[[6a91]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6a91]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/American_cockroach American cockroach] and [http://en.wikipedia.org/wiki/Digca Digca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A91 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6A91 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6a91]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Diguetia_canities Diguetia canities] and [https://en.wikipedia.org/wiki/Periplaneta_americana Periplaneta americana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A91 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6A91 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9SL:[(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl+carbamate'>9SL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6a91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a91 OCA], [http://pdbe.org/6a91 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6a91 RCSB], [http://www.ebi.ac.uk/pdbsum/6a91 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6a91 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9SL:[(3~{a}~{S},4~{R},10~{a}~{S})-2,6-bis(azanyl)-10,10-bis(oxidanyl)-3~{a},4,8,9-tetrahydro-3~{H}-pyrrolo[1,2-c]purin-4-yl]methyl+carbamate'>9SL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6a91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a91 OCA], [https://pdbe.org/6a91 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6a91 RCSB], [https://www.ebi.ac.uk/pdbsum/6a91 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6a91 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SCNA1_PERAM SCNA1_PERAM]] Mediates the voltage-dependent sodium ion permeability of excitable membranes.[RuleBase:RU361132]<ref>PMID:28183995</ref>
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[https://www.uniprot.org/uniprot/SCNA1_PERAM SCNA1_PERAM] Mediates the voltage-dependent sodium ion permeability of excitable membranes.[RuleBase:RU361132]<ref>PMID:28183995</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</SX>
</SX>
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[[Category: American cockroach]]
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[[Category: Diguetia canities]]
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[[Category: Digca]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chin, Y K.Y]]
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[[Category: Periplaneta americana]]
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[[Category: Cristofori-Armstrong, B]]
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[[Category: Chin YKY]]
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[[Category: Jiang, Y]]
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[[Category: Cristofori-Armstrong B]]
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[[Category: King, G F]]
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[[Category: Jiang Y]]
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[[Category: Lei, J L]]
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[[Category: King GF]]
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[[Category: Pan, X J]]
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[[Category: Lei JL]]
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[[Category: Shen, H Z]]
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[[Category: Pan XJ]]
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[[Category: Smith, J J]]
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[[Category: Shen HZ]]
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[[Category: Wu, J P]]
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[[Category: Smith JJ]]
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[[Category: Yan, N]]
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[[Category: Wu JP]]
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[[Category: Zhou, Q]]
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[[Category: Yan N]]
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[[Category: Li, Z Q]]
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[[Category: Zhou Q]]
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[[Category: Complex]]
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[[Category: Li ZQ]]
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[[Category: Membrane protein]]
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[[Category: Membrane protein-toxin complex]]
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[[Category: Sodium channel]]
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[[Category: Toxin]]
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Current revision

Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with saxitoxin and Dc1a

6a91, resolution 3.20Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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