7cq7

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Current revision (06:00, 3 July 2025) (edit) (undo)
 
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====
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==Structure of the human CLCN7-OSTM1 complex with ADP==
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<StructureSection load='7cq7' size='340' side='right'caption='[[7cq7]]' scene=''>
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<StructureSection load='7cq7' size='340' side='right'caption='[[7cq7]], [[Resolution|resolution]] 3.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7cq7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CQ7 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7cq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cq7 OCA], [http://pdbe.org/7cq7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7cq7 RCSB], [http://www.ebi.ac.uk/pdbsum/7cq7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7cq7 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cq7 OCA], [https://pdbe.org/7cq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cq7 RCSB], [https://www.ebi.ac.uk/pdbsum/7cq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cq7 ProSAT]</span></td></tr>
</table>
</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/OSTM1_HUMAN OSTM1_HUMAN] Infantile osteopetrosis with neuroaxonal dysplasia. The disease is caused by variants affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/OSTM1_HUMAN OSTM1_HUMAN] Required for osteoclast and melanocyte maturation and function.<ref>PMID:21527911</ref>
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==See Also==
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*[[Ion channels 3D structures|Ion channels 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Jia YT]]
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[[Category: Lei JL]]
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[[Category: Li XM]]
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[[Category: Lu YM]]
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[[Category: Yang GH]]
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[[Category: Zhang YM]]

Current revision

Structure of the human CLCN7-OSTM1 complex with ADP

PDB ID 7cq7

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