7vab

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Current revision (06:17, 3 July 2025) (edit) (undo)
 
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====
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==Cryo-EM structure of the non-acylated tirzepatide (LY3298176)-bound human GIPR-Gs complex==
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<StructureSection load='7vab' size='340' side='right'caption='[[7vab]]' scene=''>
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<StructureSection load='7vab' size='340' side='right'caption='[[7vab]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7vab]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VAB FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vab OCA], [https://pdbe.org/7vab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vab RCSB], [https://www.ebi.ac.uk/pdbsum/7vab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vab ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIB:ALPHA-AMINOISOBUTYRIC+ACID'>AIB</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vab OCA], [https://pdbe.org/7vab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vab RCSB], [https://www.ebi.ac.uk/pdbsum/7vab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vab ProSAT]</span></td></tr>
</table>
</table>
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==See Also==
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*[[Glucose-dependent Insulinotropic Polypeptide Receptor|Glucose-dependent Insulinotropic Polypeptide Receptor]]
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*[[Transducin 3D structures|Transducin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bos taurus]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Rattus norvegicus]]
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[[Category: Synthetic construct]]
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[[Category: Chang RL]]
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[[Category: Chen LN]]
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[[Category: Chen Y]]
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[[Category: Cong ZT]]
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[[Category: Dai AT]]
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[[Category: Feng WB]]
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[[Category: Hang KN]]
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[[Category: Liang AY]]
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[[Category: Ming QQ]]
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[[Category: Wang M]]
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[[Category: Wang MW]]
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[[Category: Wu BL]]
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[[Category: Xia T]]
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[[Category: Xu HE]]
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[[Category: Xu PY]]
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[[Category: Yang DH]]
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[[Category: Zhang C]]
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[[Category: Zhang Y]]
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[[Category: Zhao FH]]
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[[Category: Zhao LH]]
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[[Category: Zhou QT]]
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[[Category: Zou XY]]

Current revision

Cryo-EM structure of the non-acylated tirzepatide (LY3298176)-bound human GIPR-Gs complex

PDB ID 7vab

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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