8k3y
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k3y OCA], [https://pdbe.org/8k3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k3y RCSB], [https://www.ebi.ac.uk/pdbsum/8k3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k3y ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k3y OCA], [https://pdbe.org/8k3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k3y RCSB], [https://www.ebi.ac.uk/pdbsum/8k3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k3y ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/A0A059VAZ3_9DEIN A0A059VAZ3_9DEIN] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.[HAMAP-Rule:MF_01973] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant
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