8w9c
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8w9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8w9c OCA], [https://pdbe.org/8w9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8w9c RCSB], [https://www.ebi.ac.uk/pdbsum/8w9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8w9c ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8w9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8w9c OCA], [https://pdbe.org/8w9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8w9c RCSB], [https://www.ebi.ac.uk/pdbsum/8w9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8w9c ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/SIN3_YEAST SIN3_YEAST] Catalytic component of the RPD3 histone deacetylase complexes RPD3C(L) and RPD3C(S) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. SIN3 has also a RPD3 independent function required for normal longevity.<ref>PMID:10388812</ref> <ref>PMID:10931932</ref> <ref>PMID:11238941</ref> <ref>PMID:12808094</ref> <ref>PMID:14711989</ref> <ref>PMID:14737171</ref> <ref>PMID:15141165</ref> <ref>PMID:15143171</ref> <ref>PMID:15722108</ref> <ref>PMID:1603074</ref> <ref>PMID:16286008</ref> <ref>PMID:1944290</ref> <ref>PMID:2233725</ref> <ref>PMID:8441414</ref> <ref>PMID:8978024</ref> <ref>PMID:9234741</ref> <ref>PMID:9572144</ref> <ref>PMID:9710596</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Current revision
Cryo-EM structure of the Rpd3S complex from budding yeast
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