9mip

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Current revision (16:25, 9 July 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9mip is ON HOLD until Paper Publication
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==CryoEM structure of the Protein Phasphatase 2A (Aalpha-B56gamma-Calpha) holoenzyme complex==
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<StructureSection load='9mip' size='340' side='right'caption='[[9mip]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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Authors: Day, A., Taylor, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9mip]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MIP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MIP FirstGlance]. <br>
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Description: CryoEM structure of the Protein Phasphatase 2A (Aalpha-B56gamma-Calpha) holoenzyme complex
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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[[Category: Day, A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mip OCA], [https://pdbe.org/9mip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mip RCSB], [https://www.ebi.ac.uk/pdbsum/9mip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mip ProSAT]</span></td></tr>
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[[Category: Taylor, D]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/2AAA_HUMAN 2AAA_HUMAN] The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis.<ref>PMID:16580887</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Day A]]
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[[Category: Taylor D]]

Current revision

CryoEM structure of the Protein Phasphatase 2A (Aalpha-B56gamma-Calpha) holoenzyme complex

PDB ID 9mip

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