9u9c
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of NDM-1 in complex with hydrolyzed amoxicillin== | |
| - | + | <StructureSection load='9u9c' size='340' side='right'caption='[[9u9c]], [[Resolution|resolution]] 1.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9u9c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9U9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9U9C FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EOR:(2~{R},4~{S})-2-[(1~{R})-1-[[(2~{R})-2-azanyl-2-(4-hydroxyphenyl)ethanoyl]amino]-2-oxidanyl-2-oxidanylidene-ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic+acid'>A1EOR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: Liu | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9u9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9u9c OCA], [https://pdbe.org/9u9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9u9c RCSB], [https://www.ebi.ac.uk/pdbsum/9u9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9u9c ProSAT]</span></td></tr> |
| - | [[Category: Shi | + | </table> |
| - | [[Category: Zhang | + | == Function == |
| + | [https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Klebsiella pneumoniae]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Liu W]] | ||
| + | [[Category: Shi X]] | ||
| + | [[Category: Zhang Q]] | ||
Current revision
Crystal structure of NDM-1 in complex with hydrolyzed amoxicillin
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