9clb

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Current revision (06:36, 16 July 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9clb is ON HOLD until Paper Publication
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==Crystal structure of Bak bound to the inhibitory aBAK==
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<StructureSection load='9clb' size='340' side='right'caption='[[9clb]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9clb]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CLB FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.86&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9clb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9clb OCA], [https://pdbe.org/9clb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9clb RCSB], [https://www.ebi.ac.uk/pdbsum/9clb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9clb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BAK_HUMAN BAK_HUMAN] In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.<ref>PMID:8521816</ref> <ref>PMID:17157251</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Synthetic construct]]
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[[Category: Arguinchona L]]
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[[Category: Baker D]]
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[[Category: Bera AK]]
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[[Category: Berger SA]]
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[[Category: Birkinshaw RW]]
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[[Category: Colman PM]]
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[[Category: Czabotar PE]]
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[[Category: Fairlie WD]]
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[[Category: Harris TJ]]
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[[Category: Kang A]]
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[[Category: Kasapgil S]]
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[[Category: Kluck R]]
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[[Category: Lee EF]]
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[[Category: Miller MS]]
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[[Category: Sankaran B]]
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[[Category: Smyth S]]
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[[Category: Tran S]]
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[[Category: Uren R]]

Current revision

Crystal structure of Bak bound to the inhibitory aBAK

PDB ID 9clb

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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