9e41

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Current revision (06:44, 16 July 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9e41 is ON HOLD until Paper Publication
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==Asymmetric unit of yPOWV==
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<StructureSection load='9e41' size='340' side='right'caption='[[9e41]], [[Resolution|resolution]] 2.83&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9e41]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Deer_tick_virus Deer tick virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9E41 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9E41 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.83&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CPL:1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>CPL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9e41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9e41 OCA], [https://pdbe.org/9e41 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9e41 RCSB], [https://www.ebi.ac.uk/pdbsum/9e41 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9e41 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8VBK7_9FLAV Q8VBK7_9FLAV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Inhibits RNA silencing by interfering with host Dicer.[ARBA:ARBA00035616] May play a role in virus budding. Exerts cytotoxic effects by activating a mitochondrial apoptotic pathway through M ectodomain. May display a viroporin activity.[ARBA:ARBA00035609]
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__TOC__
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</StructureSection>
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[[Category: Deer tick virus]]
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[[Category: Large Structures]]
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[[Category: Das S]]
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[[Category: Hafenstein S]]

Current revision

Asymmetric unit of yPOWV

PDB ID 9e41

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