9goc

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Current revision (06:47, 16 July 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9goc is ON HOLD until Paper Publication
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==Crystal structure of DPP9 Ser730Ala in complex with sulphostin.==
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<StructureSection load='9goc' size='340' side='right'caption='[[9goc]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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Authors: Sewald, L., Tabak, W.W.A., Fehr, L., Zolg, S., Najdzion, M., Verhoef, C.J.A., Podlesainski, D., Geiss-Friedlander, R., Lammens, A., Kaschani, F., Hellerschmied, D., Huber, R., Kaiser, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9goc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GOC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GOC FirstGlance]. <br>
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Description: Crystal structure of DPP9 Ser730Ala in complex with sulphostin.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1INE:[azanyl-[(3~{S})-3-azanyl-2-oxidanylidene-piperidin-1-yl]phosphoryl]sulfamic+acid'>A1INE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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[[Category: Tabak, W.W.A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9goc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9goc OCA], [https://pdbe.org/9goc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9goc RCSB], [https://www.ebi.ac.uk/pdbsum/9goc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9goc ProSAT]</span></td></tr>
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[[Category: Kaschani, F]]
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</table>
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[[Category: Podlesainski, D]]
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== Disease ==
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[[Category: Sewald, L]]
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[https://www.uniprot.org/uniprot/DPP9_HUMAN DPP9_HUMAN] Idiopathic pulmonary fibrosis.
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[[Category: Najdzion, M]]
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== Function ==
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[[Category: Verhoef, C.J.A]]
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[https://www.uniprot.org/uniprot/DPP9_HUMAN DPP9_HUMAN] Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2.
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[[Category: Fehr, L]]
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__TOC__
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[[Category: Kaiser, M]]
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</StructureSection>
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[[Category: Zolg, S]]
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[[Category: Homo sapiens]]
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[[Category: Hellerschmied, D]]
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[[Category: Large Structures]]
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[[Category: Lammens, A]]
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[[Category: Fehr L]]
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[[Category: Huber, R]]
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[[Category: Geiss-Friedlander R]]
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[[Category: Geiss-Friedlander, R]]
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[[Category: Hellerschmied D]]
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[[Category: Huber R]]
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[[Category: Kaiser M]]
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[[Category: Kaschani F]]
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[[Category: Lammens A]]
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[[Category: Najdzion M]]
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[[Category: Podlesainski D]]
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[[Category: Sewald L]]
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[[Category: Tabak WWA]]
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[[Category: Verhoef CJA]]
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[[Category: Zolg S]]

Current revision

Crystal structure of DPP9 Ser730Ala in complex with sulphostin.

PDB ID 9goc

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