9bot

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Current revision (08:03, 16 July 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9bot is ON HOLD until Paper Publication
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==Human mesotrypsin (PRSS3) unliganded and in autoinhibited (E*) conformation==
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<StructureSection load='9bot' size='340' side='right'caption='[[9bot]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9bot]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9BOT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9BOT FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9bot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9bot OCA], [https://pdbe.org/9bot PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9bot RCSB], [https://www.ebi.ac.uk/pdbsum/9bot PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9bot ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRY3_HUMAN TRY3_HUMAN] Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5.<ref>PMID:12021776</ref> <ref>PMID:14507909</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Coban M]]
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[[Category: Radisky ES]]
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[[Category: Sankaran B]]

Current revision

Human mesotrypsin (PRSS3) unliganded and in autoinhibited (E*) conformation

PDB ID 9bot

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