Glycerol kinase

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Current revision (09:48, 21 July 2025) (edit) (undo)
 
Line 35: Line 35:
**[[6k76]] – TkGK + AMPPNP<br />
**[[6k76]] – TkGK + AMPPNP<br />
**[[6k78]], [[6k79]] – TkGK + glycerol <br />
**[[6k78]], [[6k79]] – TkGK + glycerol <br />
 +
**[[8pry]] – GK + glycerol – ''Trypanosoma cruzi''<br />
*Glycerol kinase ternary complex
*Glycerol kinase ternary complex
Line 50: Line 51:
**[[3wxj]] – TbGK + glycerol + G3P<br />
**[[3wxj]] – TbGK + glycerol + G3P<br />
**[[3wxl]], [[6j9v]] – TbGK + glycerol + ADP<br />
**[[3wxl]], [[6j9v]] – TbGK + glycerol + ADP<br />
 +
**[[8y1t]] – TbGK + glycerol + ADP + G3P<br />
**[[6j9q]] – TbGK + glycerol + AMPPNP<br />
**[[6j9q]] – TbGK + glycerol + AMPPNP<br />
**[[5azi]], [[5azj]] – TbGK + glycerol + nitrophenyl-phosphate<br />
**[[5azi]], [[5azj]] – TbGK + glycerol + nitrophenyl-phosphate<br />

Current revision

Glycerol kinase complex with glycerol (PDB entry 1xup)

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3D structures of glycerol kinase

Updated on 21-July-2025

References

  1. Kralova I, Rigden DJ, Opperdoes FR, Michels PA. Glycerol kinase of Trypanosoma brucei. Cloning, molecular characterization and mutagenesis. Eur J Biochem. 2000 Apr;267(8):2323-33. PMID:10759857
  2. Sehgal A, Stack J. Complex glycerol kinase deficiency: an X-linked disorder associated with adrenal hypoplasia congenita. Indian J Pediatr. 2005 Jan;72(1):67-9. PMID:15684452
  3. Yeh JI, Charrier V, Paulo J, Hou L, Darbon E, Claiborne A, Hol WG, Deutscher J. Structures of enterococcal glycerol kinase in the absence and presence of glycerol: correlation of conformation to substrate binding and a mechanism of activation by phosphorylation. Biochemistry. 2004 Jan 20;43(2):362-73. PMID:14717590 doi:10.1021/bi034258o

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