1w9n

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1w9n.gif|left|200px]]
[[Image:1w9n.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1w9n |SIZE=350|CAPTION= <scene name='initialview01'>1w9n</scene>
+
The line below this paragraph, containing "STRUCTURE_1w9n", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=2OP:(2S)-2-HYDROXYPROPANOIC+ACID'>2OP</scene>, <scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBU:(2E)-2-AMINOBUT-2-ENOIC+ACID'>DBU</scene>, <scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1w9n| PDB=1w9n | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w9n OCA], [http://www.ebi.ac.uk/pdbsum/1w9n PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1w9n RCSB]</span>
+
-
}}
+
'''ISOLATION AND CHARACTERIZATION OF EPILANCIN 15X, A NOVEL ANTIBIOTIC FROM A CLINICAL STRAIN OF STAPHYLOCOCCUS EPIDERMIDIS'''
'''ISOLATION AND CHARACTERIZATION OF EPILANCIN 15X, A NOVEL ANTIBIOTIC FROM A CLINICAL STRAIN OF STAPHYLOCOCCUS EPIDERMIDIS'''
Line 32: Line 29:
[[Category: Nuland, N A.J Van.]]
[[Category: Nuland, N A.J Van.]]
[[Category: Verhoef, J.]]
[[Category: Verhoef, J.]]
-
[[Category: lanthionine-ring]]
+
[[Category: Lanthionine-ring]]
-
[[Category: lantibiotic]]
+
[[Category: Lantibiotic]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 13:21:07 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:33:10 2008''
+

Revision as of 10:21, 3 May 2008

Image:1w9n.gif

Template:STRUCTURE 1w9n

ISOLATION AND CHARACTERIZATION OF EPILANCIN 15X, A NOVEL ANTIBIOTIC FROM A CLINICAL STRAIN OF STAPHYLOCOCCUS EPIDERMIDIS


Overview

The potential application of lantibiotics as food-preserving agents and more recently as antibiotics has strongly increased the interest in these antibacterial peptides. Here, we report the elucidation of the primary and three-dimensional structures of the novel lantibiotic epilancin 15X from Staphylococcus epidermidis using high-resolution nuclear magnetic resonance spectroscopy and tandem mass spectrometry. The molecule contains ten post-translationally modified amino acids, three lanthionine ring structures and a hydroxy-propionyl N-terminal moiety. The primary and tertiary structure and the distribution of positive charges are closely similar to the previously identified lantibiotic epilancin K7, most likely indicative of a common mode of action.

About this Structure

1W9N is a Single protein structure of sequence from Staphylococcus epidermidis. Full crystallographic information is available from OCA.

Reference

Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis., Ekkelenkamp MB, Hanssen M, Danny Hsu ST, de Jong A, Milatovic D, Verhoef J, van Nuland NA, FEBS Lett. 2005 Mar 28;579(9):1917-22. PMID:15792796 Page seeded by OCA on Sat May 3 13:21:07 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1w9n"
Personal tools